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KMID : 0374019800030020063
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Ewha Medical Journal
1980 Volume.3 No. 2 p.63 ~ p.67
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Hepatic Microsomal Cytochrome P-450 Levels During Preimplantation in Rats
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Abstract
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The levels of hepatic microsomal cytochrome P-450 in preimplantation rats were determined
1) The activities of the hepatic microsomal cytochrome P-450 associated with the
events leading to implantation were gradually increased in preimplantation rats.
2) The level of the hepatic microsomal cytochrome P-450 was peak, 2.65 nmoles/mg
protein, on day 4 in normal preimplantation rat.
3) The activity of the hepatic microsomal cytochrome P-450 was decreased in ovariectomized rat than the normal rata
4) The hepatic microsomal cytochrome P-450 level in ovariectomized rat was peak, 2.39 nmoles; mg protein, on day 5.
5) We observed the fact that the activity of microsomal P-450 was delayed in ovariectomized rat.
6) We confirmed the fact that the hepatic microsomal cytochrome P-450 level was affected by steroid hormone.
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